Gene therapy for

Muscular

Dystrophies

   

Epigenetic Gene Regulation

ABOUT Episwitch Rx

EpiSwitch Rx is a gene therapy biotechnology company developing therapeutics for neuromuscular conditions.

 

We are developing epigenetic tools to treat the root cause of disease. 

Our most advanced pre-clinical program is a CRISPR-based approach to treat the underlying cause of FSHD (facio scapulo humeral muscular dystrophy) which affects over 1m people worldwide.

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Our Mission

Our vision is to bring new treatments and therapies to patients with muscle disorders.

There are over 5.5m people affected by a muscular dystrophy.  

In many cases these are Orphan or Rare Diseases and there are no available treatment options.                                        By bringing together the best scientists, KOL's and disease experts and working directly with patient communities, clinicians, payors and other health stakeholders, we hope to make a transformational difference and change lives. 

 
 

FSHD (facioscapulohumeral muscular dystrophy)

FSHD is an epigenetic gain-of-function neuromuscular disorder caused by the misexpression of DUX4 protein in skeletal muscle

CRISPRi Therapy for FSHD

CRISPR inhibition restores a more normal state of epigenetic repression at the DUX4 gene, making it an ideal candidate for FSHD therapy

     

 

 This Web site may contain general information relating to various medical conditions and their treatment. Such information is provided for informational purposes only and is not meant to be a substitute for advice provided by a doctor or other qualified health care professional. Patients should not use the information contained herein for diagnosing a health problem or disease. Patients should always consult with a doctor or other health care professional for medical advice or information about diagnosis and treatment.

© 2021 EpiSwitch Rx

450 Sinclair Street

ML 0724  NV 89501

USA

Mail: info@episwitchrx.com